THE ROLE OF CYCLIC 3′:5′-ADENOSINE MONOPHOSPHATE IN THE RESPONSES OF THE INTESTINE AND KIDNEY TO ANGIOTENSIN

Abstract
In this study of the possible involvement of cyclic AMP in the responses of a variety of transporting epithelia, angiotensin had no effect on cyclic AMP contents or on adenylatecyclase activities of the tissue investigated, namely in vitro preparations of rat colon and kidney cortex. It appears likely that angiotensin is a rare example of a polypeptide hormone which does not act by either increasing or decreasing the activity of the adenylatecyclase system.

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