Histopathological changes following removal of the perineurium

Publisher Website
Google Scholar
Abstract
Using microsurgical techniques, the perineurial sheath was stripped off rat sciatic nerves over a 0.5 cm length at a point where the nerve consists of a single fascicle. The nerves were excised 0-84 days after the injury and were examined in semi-thin transverse section. A new sheath closely resembling normal perineurium became organized during the first 10 days; it appeared uniformly over the length of the injured segment. The regenerated perineurial sheath was probably formed by endoneurial fibroblasts migrating from within the fascicle. In undamaged specimens the axons immediately beneath the exercised perineurium underwent no degenerative changes.

This publication has 14 references indexed in Scilit: