Thyroid hormone administration in irradiated patients

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Abstract
In a recall clinic for patients at risk for thyroid carcinoma due to a history of radiation in infancy or childhood, a group of patients were randomly offered prospective suppressive L‐thyroxine therapy and matched to a radiated nontreated group. With an average of more than two years' follow‐up, the thyroid hormone‐treated radiated group developed fewer nodules and abnormalities to palpation and also had a statistically significant lessening of minimal palpable abnormalities compared to the nonthyroxine‐treated radiated group.