Plant Anticancer Agents. XXIV. Alkaloid Constituents of Simaba multiflora

Abstract
Two new cytotoxic canthin-6-ones, 10-methoxycanthin-6-one (1) and 10-hydroxycanthin-6-one (2) were isolated from the wood of S. multiflora (Simaroubaceae). Three canthin-2,6-diones, 10-hydroxy-3-methoxycanthin-2,6-dione (3), 3-methoxycanthin-2,6-dione (4) and canthin-2,6-dione (5), and scopoletin (7) and the novel coumarino-lignain cleomiscosin A (6) were also obtained.

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