NABILONE - POTENT ANTI-EMETIC CANNABINOL WITH MINIMAL EUPHORIA

Google Scholar
  • 1 January 1977
    • journal article
    • research article
    • Vol. 27  (9-10) , 331-334
Abstract
Nabilone is a cannabinol derivative which has potent central antiemetic effects in animals. The drug significantly reduced the nausea and vomiting induced by cancer chemotherapy in 10 of 13 patients who were refractory to conventional antiemetics. A dose-response effect was apparent. The drug was generally well-tolerated, although it also had sedative effects. Additionally, dizziness, decreased and coordination and postural hypotension were observed in some patients. Euphoric effects of the agent were minimal at antiemetic dosage levels.

This publication has 1 reference indexed in Scilit: