Cyprinid Herpesvirus 3
Open Access
- 1 December 2010
- journal article
- research article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 16 (12) , 1835-1843
- https://doi.org/10.3201/eid1612.100593
Abstract
The recently designated cyprinid herpesvirus 3 (CyHV-3) is an emerging agent that causes fatal disease in common and koi carp. Since its emergence in the late 1990s, this highly contagious pathogen has caused severe financial losses in common and koi carp culture industries worldwide. In addition to its economic role, recent studies suggest that CyHV-3 may have a role in fundamental research. CyHV-3 has the largest genome among viruses in the order Herpesvirales and serves as a model for mutagenesis of large DNA viruses. Other studies suggest that the skin of teleost fish represents an efficient portal of entry for certain viruses. The effect of temperature on viral replication suggests that the body temperature of its poikilotherm host could regulate the outcome of the infection (replicative vs. nonreplicative). Recent advances with regard to CyHV-3 provide a role for this virus in fundamental and applied research.Keywords
This publication has 35 references indexed in Scilit:
- Herpesvirus assembly: An updateVirus Research, 2009
- The Major Portal of Entry of Koi Herpesvirus in Cyprinus carpio Is the SkinJournal of Virology, 2009
- The order HerpesviralesArchiv für die gesamte Virusforschung, 2008
- Cloning of the Koi Herpesvirus Genome as an Infectious Bacterial Artificial Chromosome Demonstrates That Disruption of the Thymidine Kinase Locus Induces Partial Attenuation in Cyprinus carpio koiJournal of Virology, 2008
- Genome Sequences of Three Koi Herpesvirus Isolates Representing the Expanding Distribution of an Emerging Disease Threatening Koi and Common Carp WorldwideJournal of Virology, 2007
- Susceptibility of cyprinid cultured cells to cyprinid herpesvirus 3Archiv für die gesamte Virusforschung, 2007
- Persistence of Cyprinid Herpesvirus 3 in Infected Cultured Carp CellsJournal of Virology, 2007
- Bioluminescence Imaging of Live Infected Salmonids Reveals that the Fin Bases Are the Major Portal of Entry for NovirhabdovirusJournal of Virology, 2006
- Differential resistance to koi herpes virus (KHV)/carp interstitial nephritis and gill necrosis virus (CNGV) among common carp (Cyprinus carpio L.) strains and crossbredsAquaculture, 2005
- A Herpesvirus Associated with Mass Mortality of Juvenile and Adult Koi, a Strain of Common CarpJournal of Aquatic Animal Health, 2000