THE PERIPHERAL NERVE FUNCTION IN CHRONIC RENAL FAILURE

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Abstract
Clinical symptoms and signs of peripheral nerve dysfunction in 109 patients with chronic renal failure have been intercorrelated. Paresthesia was the symptom best correlated to signs favouring a neuropathy, whereas cramps and restless legs occurred equally frequently in patients with and without signs. The discriminant power of each single symptom and sign for the detection of peripheral neuropathy was analysed. The results indicate that 91% of all patients presenting neurological findings would be detected when any one of the following three criteria are present alone or in combination: paresthesia, impaired vibratory perception, and reflex disturbances. A grading of clinical findings into three groups (eight classes) is presented, according to the number of symptoms and signs, severity and extent of neurological affection.

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