Association Between the T29→C Polymorphism in the Transforming Growth Factor β1 Gene and Breast Cancer Among Elderly White Women
Open Access
- 13 June 2001
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 285 (22) , 2859-2863
- https://doi.org/10.1001/jama.285.22.2859
Abstract
Family history is a known risk factor for the development of breast cancer.1 Two genes (BRCA1 and BRCA2) associated with markedly increased risk of breast cancer have been identified, but mutations in these genes are relatively uncommon and account for a small fraction of breast cancer.2,3 Therefore, other genes are likely to modify the risk of breast cancer.4Keywords
This publication has 8 references indexed in Scilit:
- High-Throughput Single Nucleotide Polymorphism Genotyping by Fluorescent 5′ Exonuclease AssayBioTechniques, 1999
- Transforming growth factor beta-1 gene polymorphism and bone mineral density in japanese adolescentsThe American Journal of Medicine, 1999
- Genetic control of the circulating concentration of transforming growth factor type beta1Human Molecular Genetics, 1999
- No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancerBritish Journal of Cancer, 1998
- Frequency of Breast Cancer Attributable to BRCA1 in a Population-Based Series of American WomenJAMA, 1998
- Bone Mass and the Risk of Breast Cancer among Postmenopausal WomenNew England Journal of Medicine, 1997
- Bone mineral density and risk of breast cancer in older women: the study of osteoporotic fractures. Study of Osteoporotic Fractures Research GroupPublished by American Medical Association (AMA) ,1996
- Mammary tumor suppression by transforming growth factor beta 1 transgene expression.Proceedings of the National Academy of Sciences, 1995