Insulin resistance and depressive symptoms in middle aged men: findings from the Caerphilly prospective cohort study

Abstract
The Caerphilly cohort study has been described in detail before.4 In phase I (1979-83), 2512 (89% of eligible) men aged 45-59 years from Caerphilly in Wales provided fasting blood samples. Insulin resistance (homoeostasis model assessment (HOMA) score) was derived from fasting insulin and glucose.5 HOMA scores were not calculated for men with diabetes or high fasting glucose (≥ 7.0 mmol/l).