Malignant transformation in oral leukoplakia

1 December 1987

journal article
research article
Published by Wiley in European Journal of Oral Sciences

Vol. 95 (6) , 449-455
https://doi.org/10.1111/j.1600-0722.1987.tb01959.x

Abstract

A retrospective study on the incidence of malignant transformation in oral leukoplakia was performed covering the period from 1970 to 1980. Carcinoma developed in 11 of the 157 patients, and this 7% incidenced increased to 8.9% when the same patients were followed prospectively for 6 more years. Dysplasia was found in biopsies from 51 patients (31.8%), and was significantly more frequent in women than men (P < 0.05). Dysplasia grade and cancer development were related to updated clinical and etiological parameters.

Keywords

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