Réactivité des N-vinylaziridines fonctionnalisées. Synthèse de dérivés des α,β-déhydro α-amino acides

Publisher Website
Google Scholar
Abstract
Secondary 2-cyano- and 2-ethoxycarbonylaziridines react with acetylenic compounds and activated vinylic chlorides to give 2-cyano and 2-ethoxycarbonyl N-vinylaziridines. The nucleophile-catalysed isomerization of these compounds generally gives α,β-dehydro α-amino acid derivatives involving nucleophilic attack at C-3. Thermal isomerization, involving predominantly cleavage of the carbon–carbon bond of the ring, forms α-vinylamino esters and nitriles.
Keywords

This publication has 0 references indexed in Scilit: