Concentrations of baclofen in serum and breast milk from a lactating woman
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 41 (2) , 185-187
- https://doi.org/10.3109/00365518109092032
Abstract
A lactating woman with spastic paraplegia was given 94 μmol (20 mg) of baclofen orally to study the transport of the drug into breast milk. The concentration of baclofen in serum and milk was determined with a gas chromatographc-mass pectrometric method. The elimination curves in serum and milk showed a similar course, the elimination from milk being delayed about 3 h relative to serum. The total amount of baclofen excreted in the milk during 24 h was about one thousandth of the ingested dose.Keywords
This publication has 2 references indexed in Scilit:
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- A new agent for the control of spasticityJournal of Neurology, Neurosurgery & Psychiatry, 1970