Natural killer-like activity in human cultured lymphoid cells propagated in the presence of interleukin-2: acquired resistance to prostaglandin E2- or dexamethasone-mediated suppression
- 1 May 1985
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 41 (5) , 667-669
- https://doi.org/10.1007/bf02007711
Abstract
The cytotoxic activity of human peripheral blood lymphocytes against the natural killer-sensitive target K562 was suppressed both by prostaglandin E2 and dexamethasone. On the other hand, cultured lymphoid cells propagated in the presence of interleukin-2 showed strong cytotoxic reactivity against K562 targets, and were resistant to prostaglandin E2- or dexamethasone-mediated suppression.Keywords
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