Nonimmune Interaction of the SfbI Protein ofStreptococcus pyogeneswith the Immunoglobulin G F(ab′)2Fragment
Open Access
- 1 August 2000
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 68 (8) , 4786-4788
- https://doi.org/10.1128/iai.68.8.4786-4788.2000
Abstract
Fibronectin-binding protein I (SfbI) ofStreptococcus pyogenesbinds to mouse immunoglobulin G (IgG) but not to IgA or IgM in a nonimmune fashion. The fibronectin-binding domains of SfbI were responsible for this activity, which was targeted to the IgG F(ab′)2fragment. SfbI also binds to B cells but not to CD4+or CD8+lymphocytes.Keywords
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