• 1 January 1978
    • journal article
    • research article
    • Vol. 45  (JUN) , 295-301
Abstract
Changes in uptake of radioactive uridine and its incorporation into RNA were determined in preimplantation mouse embryos, from the 2-cell to the blastocyst stage, as a measure of their responsiveness to extracellular conditions. Two media were tested, 1 contained serum and the other contained bovine serum albumin as a control. An increase in the acid-soluble pool occurred at the 8-cell stage and a marked increase in RNA synthesis occurred at the early blastocyst stage when the embryos were incubated with serum.