ADAPTATION TO EXPERIMENTAL MOTION SICKNESS IN DOGS

Publisher Website
Google Scholar
Abstract
Dogs which have been used for repeated tests on motion sickness show a gradual adaptation to motion on a swing. This refractoriness varies in extent, but is most readily produced in dogs having low initial susceptibility to motion. Highly susceptible animals may show only little change to swinging every 5 days over a 3-yr. period. Although swinging every 7 days may cause adaptation, the state rapidly follows daily or twice-daily swingings. The speed of development is apparently proportional to the number of exposures. Some evidence is presented that adaptation occurs more rapidly when the duration of swinging is increased. Treatment with prostigmine or hyoscind did not inhibit or enhance adaptation to motion. Adaptation to motion took place and was maintained even though a dog was effectively treated by the barbiturate V-12, ethyl beta-methyl allyl thiobarbituric acid. Conditioned vomiting to the swing was not observed. One animal of another worker showed this reaction which was prevented by treatment with V-12.

This publication has 3 references indexed in Scilit: