Prenatal diagnosis and gonadal findings in X/XXX mosaicism.

Abstract
Prenatal diagnosis of a case of X/XXX mosaicism is presented. Despite the fact that over 50% of the cells cultured from both ovaries were trisomic for the X chromosome, fetal oocytes were rarely found. The presence of a triple-X cell line, even in a relatively high percentage of ovarian cells, does not necessarily protect the ovary from aoogenesis. This observation might prove useful in the counseling of future cases involving the prenatal detection of sex chromosome mosaicism.