Serum Markers in Testicular Tumors

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Abstract
Certain cancer-associated substances are useful in the diagnosis and management of cancer. The estimation of serum .alpha.-fetoprotein and .beta.-human chorionic gonadotropin in patients with testicular tumors is useful. Of 17 patients with germ cell testicular tumors found to have elevated serum markers, 3 had seminoma of the testis and all 3 had elevated .beta.-human chorionic gonadotropin. It is not possible to correlate the histology of testicular tumors and the type of serum markers. All patients with elevated markers had active tumor. However, 3 patients with metastatic deposits in the para-aortic lymph nodes did not have elevated serum markers.