AMPK: A Key Sensor of Fuel and Energy Status in Skeletal Muscle
Top Cited Papers
- 1 February 2006
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 21 (1) , 48-60
- https://doi.org/10.1152/physiol.00044.2005
Abstract
Contraction induces marked metabolic changes in muscle, and the AMP-activated protein kinase (AMPK) is a good candidate to explain these effects. Recent work using a muscle-specific knockout of the upstream kinase, LKB1, has confirmed that the LKB1→AMPK cascade is the signaling pathway responsible for many of these effects.Keywords
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