Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice
Open Access
- 1 March 2009
- journal article
- research article
- Published by Elsevier in Journal of Lipid Research
- Vol. 50 (3) , 412-423
- https://doi.org/10.1194/jlr.m800383-jlr200
Abstract
No abstract availableKeywords
This publication has 62 references indexed in Scilit:
- Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition*Journal of Lipid Research, 2008
- Loss of functional ELOVL4 depletes very long-chain fatty acids (≥C28) and the unique ω-O-acylceramides in skin leading to neonatal deathHuman Molecular Genetics, 2007
- Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesityJournal of Lipid Research, 2006
- Protein Sensors for Membrane SterolsCell, 2006
- Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genesProceedings of the National Academy of Sciences, 2003
- The enzymic chain elongation of fatty acids by rat-liver microsomesPublished by Elsevier ,2002
- Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1cJournal of Biological Chemistry, 2002
- REGULATION OF GENE EXPRESSION BY DIETARY FATAnnual Review of Nutrition, 1999
- Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.Journal of Clinical Investigation, 1997
- Dietary polyunsaturated fatty acid regulation of gene transcriptionProgress in Lipid Research, 1996