MARFAN'S SYNDROME IN THE ADULT
- 1 October 1947
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 80 (4) , 475-490
- https://doi.org/10.1001/archinte.1947.00220160054005
Abstract
ARACHNODACTYLY (Marfan's syndrome) is a relatively rare familial symptom complex which is familiar to ophthalmologists, pediatricians and, to a lesser extent, orthopedic surgeons. It should be of interest to all physicians. We wish to summarize its important characteristics and emphasize the aortic lesions which may be associated with it. REVIEW OF THE LITERATURE Although entitled dolichostenomelie by Marfan,1Archard2in 1902 emphasized the most characteristic feature of the syndrome, calling it arachnodactyly (spider fingers). In 1926 Piper and Irving-Jones,3the first American physicians to record the condition, noted the frequency with which it is associated with congenital malformations of the heart. Futcher and Southworth4in 1938 pointed out rheumatic endocarditis and pulmonary disorders as common medical complications. In 1943 Baer, Taussig and Oppenheimer5reported 2 cases in which aneurysmal dilatation of the aorta was found at autopsy. The same year Etter and Glover6This publication has 0 references indexed in Scilit: