Neuroprotective actions of peripherally administered insulin‐like growth factor I in the injured olivo‐cerebellar pathway
- 1 June 1999
- journal article
- research article
- Published by Wiley in European Journal of Neuroscience
- Vol. 11 (6) , 2019-2030
- https://doi.org/10.1046/j.1460-9568.1999.00623.x
Abstract
Exogenous administration of insulin-like growth factor I (IGF-I) restores motor function in rats with neurotoxin-induced cerebellar deafferentation. We first determined that endogenous IGFs are direc...Keywords
This publication has 50 references indexed in Scilit:
- Insulin-like growth factor I protects and rescues hippocampal neurons against β-amyloid- and human amylin-induced toxicityProceedings of the National Academy of Sciences, 1997
- GAP-43: an intrinsic determinant of neuronal development and plasticityTrends in Neurosciences, 1997
- Insulin-like growth factor I modulates c-fos induction and astrocytosis in response to neurotoxic insultNeuroscience, 1996
- Expression of NCAM and its polysialylated isoforms during mdx mouse muscle regeneration and in vitro myogenesisNeuromuscular Disorders, 1994
- Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.Proceedings of the National Academy of Sciences, 1993
- Characterization of insulin-like growth factor binding proteins by two-dimensional polyacrylamide gel electrophoresis and ligand blot analysisAnalytical Biochemistry, 1992
- A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injuryBiochemical and Biophysical Research Communications, 1992
- Receptor‐mediated endocytosis and degradation of insulin‐like growth factor I and II in neonatal rat astrocytesJournal of Neuroscience Research, 1992
- Ontogeny of Serum Insulin-Like Growth Factor Binding Proteins in the Rat*Endocrinology, 1989
- Central neurotoxic effects of intraperitoneally administered 3-acetylpyridine, harmaline and niacinamide in Sprague-Dawley and Long-Evans rats: A critical review of central 3-acetylpyridine neurotoxicityBrain Research Reviews, 1985