Absence of Cardiac Toxicity of Zidovudine in Infants
- 14 September 2000
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 343 (11) , 759-766
- https://doi.org/10.1056/nejm200009143431102
Abstract
Some evidence suggests that perinatal exposure to zidovudine may cause cardiac abnormalities in infants. We prospectively studied left ventricular structure and function in infants born to mothers infected with the human immunodeficiency virus (HIV) in order to determine whether there was evidence of zidovudine cardiac toxicity after perinatal exposure.Keywords
This publication has 13 references indexed in Scilit:
- Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analoguesThe Lancet, 1999
- Lack of Long-term Effects of In Utero Exposure to Zidovudine Among Uninfected Children Born to HIV-Infected WomenJAMA, 1999
- Fetal Cardiorespiratory and Neurobehavioral Response to Zidovudine (AZT) in the BaboonJournal of the Society for Gynecologic Investigation, 1997
- Zidovudine Therapy and Left Ventricular Function and Mass in Human Immunodeficiency Virus-Infected PatientsCardiology, 1997
- Clinical Approach to Genetic Cardiomyopathy in ChildrenCirculation, 1996
- Mitochondrial function in children with idiopathic dilated cardiomyopathyJournal of Inherited Metabolic Disease, 1995
- Effect of zidovudine and didanosine treatment on heart function in children infected with human immunodeficiency virusThe Journal of Pediatrics, 1995
- Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine TreatmentNew England Journal of Medicine, 1994
- Limitations of fractional shortening as an index of contractility in pediatric patients infected with human immunodeficiency virusThe Journal of Pediatrics, 1994
- Cardiac Structure and Function in Children with Human Immunodeficiency Virus Infection Treated with ZidovudineNew England Journal of Medicine, 1992