Abstract
An improved adhesive patch is described, capable of collecting sweat continuously at a steady rate for periods up to 10 days. Normal human subjects (4) wore duplicate patches applied to the skin above the outer ankle and the collecting pads were weighed every 2nd day for 10 days. Uptake was linear in all patches (r2 [regression coefficient] = 0.99) and the uptake rate varied from 18.38 to 47.01 mg/day (mean = 27.18 mg/day, equivalent to 0.71 mg/cm2 per hour). Several drugs are excreted in the sweat, and this patch has potential applications as a tool to monitor drug-taking behavior.

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