Acute Vascular Lesions Produced by Selected Non-pressor Rental Cortical Extracts
Open Access
- 1 January 1966
- journal article
- Published by Japanese Circulation Society in Japanese Circulation Journal
- Vol. 30 (5) , 539-542
- https://doi.org/10.1253/jcj.30.539
Abstract
Pressor and non-pressor aqueous extracts were separated from normal and ischemic rabbit kidney cortex by column chromatography and injected into test animals. Five to 6 test animals injected with the non-pressor extract from ischemic kidney developed vascular injuries especially in small cerebral arteries. This finding suggests that a non-pressor substance capable of producing vascular injury independent of renin is present in ischemic kidney cortex.Keywords
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