STEROID EXCRETION IN ANOREXIA NERVOSA PATIENTS

Abstract
Seven anorexia nervosa (AN) patients had reduced urinary excretion values of tetrahydrocortisone (THE), androsterone (A) and 5.alpha.-tetrahydrocortisol (5.alpha.-THF). THE to tetrahydrocortisol (THF), A to etiocholanolone (Ae) and 5.alpha.-THF to THF ratios were all significantly reduced. Six AN patients had oral metyrapone tests with quantitatively normal but delayed urinary 3.alpha.,17.alpha.,21-trihydroxy-5.beta.-pregnan-20-one (THS) response. The steroid determinations were done by capillary gas chromatography, which was of value in the study of the metabolic abnormalities.

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