The New HLA Nomenclature
- 29 April 1976
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 294 (18) , 1005-1006
- https://doi.org/10.1056/nejm197604292941812
Abstract
For many years it has been appreciated that there is an antigenic system of major importance as a barrier to successful allotransplantation. A major histocompatibility complex (MHC) of several closely linked genes is in fact present in all species studied so far, and a number of homologies between the human HLA system and the well defined H-2 MHC of the mouse have been demonstrated.1 HLA has been shown by family studies and somatic cell hybridization experiments to be on the sixth chromosome. A number of recent discoveries regarding the fine structure of the HLA MHC have made it essential that . . .Keywords
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