Measles Meningoencephalitis

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Abstract
Introduction The central nervous system complications of measles were recognized as early as 1872, when Westphal first used the term acute disseminated encephalomyelitis. Measles encephalitis as a clinical entity was very adequately described by Neal and Appelbaum, in 1927,4and by Musser and Hauser, in 1928.7An increasing interest in the subject of measles encephalitis in recent years has stimulated a search for some form of specific therapy. In 1952, corticotropin (ACTH) was first tried in a series of patients by Appelbaum, at Willard Parker.* Gamma-globulin has subsequently been tried in the treatment of measles encephalitis; however, experience has indicated that it is not an effective therapeutic agent.6 The purpose of this presentation is to summarize the experience over a 10-year period with measles meningoencephalitis occurring in the pediatric age group at Grasslands Hospital. There have been 24 diagnosed cases of measles meningoencephalitis treated here since 1945,

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