Immunological characterization of the endoproteases PC1 and PC2 in adrenal chromaffin granules and in the pituitary gland
- 10 February 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 297 (3) , 302-305
- https://doi.org/10.1016/0014-5793(92)80560-4
Abstract
Specific antisera against synthetic Fragments of the endoproteases, PC1 and PC2, were used to characterize these proteins. In one-dimensional immunoblots these antisera labelled components of 85 kDa for PC1 and of 70 kDa for PC2 in purified bovine chromaffin granules and anterior and posterior pituitary of ox and rat. In membranes of bovine chromaffin granules glycoprotein H was identified as the major PC2 immunoreactive spot. A major part of these endoproteases appeared membrane bound.Keywords
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