STAGE-II CARCINOMA OF ENDOMETRIUM - ANALYSIS OF TREATMENT

  • 1 January 1978
    • journal article
    • research article
    • Vol. 52  (1) , 97-99
Abstract
An analysis of 41 patients with histologically documented stage II adenocarcinoma of the endometrium treated between 1969 and 1974 is presented. The 3-yr survival for all patients was 46%. Patients treated with radiation therapy alone (tandem, ovoids and external radiation therapy) had 29% survival while patients treated with radiation therapy and surgery had a 71% survival. For all patients, survival by grade was 80% (grade I), 36% (grade II) and 20% (grade III). Among those patients with recurrent disease, 40% of cases were in the pelvis while 20% were isolated distal recurrences. Patients with stromal invasion of the cervix had a 30% survival while patients without stromal invasion had a 67% survival. An analysis of these data, along with a review of the literature, reveals that hysterectomy plays a critical role in survival, invasion of the cervical stroma would appear to be a requisite criteria for the establishment of stage II disease and aggressive radiation therapy with uterine packings (Heyman capsules) should be attempted in those patients who are not surgical candidates.

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