Structure re-assignment of a metabolite of ampicillin and amoxycillin and epimerization of their penicilloic acids
- 1 March 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 35 (3) , 138-143
- https://doi.org/10.1111/j.2042-7158.1983.tb04292.x
Abstract
Products formed in-vitro from ampicillin and amoxycillin penicilloates have been examined by high-performance liquid chromatography, ultraviolet and nuclear magnetic resonance spectroscopy and thiol group determination and were found to be the 5S epimers of the penicilloic acids. This is in contrast to a published claim that the corresponding penamaldic acids were formed by the treatment used.This publication has 13 references indexed in Scilit:
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