What Improves with Increased Missing Data Imputations?

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Abstract
When using multiple imputation in the analysis of incomplete data, a prominent guideline suggests that more than 10 imputed data values are seldom needed. This article calls into question the optimism of this guideline and illustrates that important quantities (e.g., p values, confidence interval half-widths, and estimated fractions of missing information) suffer from substantial imprecision with a small number of imputations. Substantively, a researcher can draw categorically different conclusions about null hypothesis rejection, estimation precision, and missing information in distinct multiple imputation runs for the same data and analysis with few imputations. This article explores the factors associated with this imprecision, demonstrates that precision improves by increasing the number of imputations, and provides practical guidelines for choosing a reasonable number of imputations to reduce imprecision for each of these quantities.

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