Long-Term Sequelae of Spontaneous Axillary–Subclavian Venous Thrombosis

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Abstract
The frequency and severity of post-thrombotic sequelae after spontaneous axillary–subclavian venous thrombosis remain poorly known. To determine the late sequelae of conventionally treated spontaneous axillary–subclavian venous thrombosis. Cross-sectional study. University department of vascular medicine. 54 patients seen during an 18-year period (mean follow-up, 5 years). Scores for the severity of post-thrombotic symptoms were graded on a numerical rating scale ranging from 0 to 10 and on a 6-point verbal rating scale. Ultrasonographic sequelae were classified as grade 0, normal flow; grade 1, moderate obstruction; or grade 2, severe obstruction or occlusion. Verbal scores were “nil/negligible” in 47% of patients and “severe/intolerable” in 13%; numerical scores were 0 to 3 in 78% of patients and 7 to 10 in 9%. Grade 2 ultrasonographic sequelae were found in 22% of cases. No relation was seen between ultrasonographic sequelae and symptom severity scores. The overall clinical outcome of spontaneous axillary–subclavian venous thrombosis is good, and there is no relation between the severity of late symptoms and ultrasonographic sequelae.