Action of Tonin on the Response of Rat on Mesenteric Vessels to Norepinephrine

Abstract
Infusion into the rat mesenteric angiotensin II directly from a natural protein plus the tetradecapeptide renin substrate, significantly potentiated the vasoconstrictor response to norepinephrine. The effect was not inhibited by the simultaneous administration of an inhibitor of angiotensin I-converting enzyme or by Sar1,Ala8-angiotensin II. These substances block the pressor effect of the angiotensins I and II, respectively.