Phytochemical Studies on the Tobacco Alkaloids. XII. Identification of γ-Methylaminobutyraldehyde and its Precursor Role in Nicotine Biosynthesis
Open Access
- 1 January 1968
- journal article
- research article
- Published by Oxford University Press (OUP) in Plant Physiology
- Vol. 43 (1) , 93-98
- https://doi.org/10.1104/pp.43.1.93
Abstract
γ-Methylaminobutyraldehyde (N-methylpyrroline) labeled with 14C was isolated from tobacco roots which had metabolized ornithine-2-14C. It was labeled most strongly 4 hours after adding ornithine-2-14C to the root, also labeled by putrescine-1,4-14C and methionine-14CH3, and observed in the root but not in the aerial portions of tobacco plants. γ-Methyl-aminobutyraldehyde when added back to the root was an efficient precursor of nicotine. Identity of γ-methylaminobutyraldehyde from tobacco roots was confirmed by comparison with the authentic compound.This publication has 7 references indexed in Scilit:
- Biosynthesis of the nicotine alkaloids in Nicotiana glutinosaArchives of Biochemistry and Biophysics, 1965
- Ornithine as a precursor for the pyrrolidine ring of nicotineBiochimica et Biophysica Acta, 1959
- Glutamate as a Precursor for the Pyrrolidine Ring of NicotineJournal of Biological Chemistry, 1958
- The Presence of Ornithine Cycle Amino Acids in Some Higher Plants.Plant Physiology, 1957
- Nicotine Production and Growth of Excised Tobacco Root Cultures.Plant Physiology, 1957
- Nature and Site of Origin of the Hyperglycæmic Substance released following an Injection of Growth HormoneNature, 1957
- The biosynthesis of the pyrrolidine ring of nicotineBiochimica et Biophysica Acta, 1955