In-vitro antigonococcal activity of rosoxacin (WIN 35213).
- 1 February 1981
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 57 (1) , 33-35
- https://doi.org/10.1136/sti.57.1.33
Abstract
The in-vitro activity of rosoxacin against 173 isolates of Neisseria gonorrhoeae, including 17 .beta.-lactamase-producers, was tested by an agar dilution method. Of the isolates, 167 (including 16 of the .beta.-lactamase-producers) were inhibited by 0.06 mg/l of rosoxacin. The remaining 6 isolates were moderately resistant to penicillin but were inhibited by 0.12-0.25 ml/l of rosoxacin. There was little correlation between the minimum inhibitory concentrations (MIC) of rosoxacin and penicillin, except for isolates with penicillin MIC of 0.06-1.00 mg/l, for which correlation was good.This publication has 5 references indexed in Scilit:
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