The behavioral effects of prenatal hypoxia in the rat

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Abstract
Pregnant rats were exposed to an oxygen depleted atmosphere (13% oxygen in nitrogen) at normal pressure in 2‐hr daily sessions extending over approximately the last 14 days of pregnancy. Their progeny were compared with control progeny in terms of age of eye‐opening, open‐field behavior, and Hebb‐Williams maze problem solving ability. The groups were not distinguishable by their performance in the open‐field, but the experimental animals opened their eyes significantly earlier and made significantly more errors on Hebb‐Williams maze problems.

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