GROWTH AND REGRESSION OF THE CORPORA LUTEA FORMED IN GUINEA-PIGS IN RESPONSE TO TREATMENT WITH EXOGENOUS GONADOTROPHIN

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Abstract
SUMMARY The growth and functional activity of luteal bodies formed in the ovaries of guinea-pigs given exogenous gonadotrophin was examined. Folliclestimulating hormone, luteinizing hormone, both hormones together, and both hormones supplemented with prolactin, were given on day 13. Vaginal oestrus occurred 8–12 days later, irrespective of the kind of hormone given. The sizes of luteal bodies induced in intact and hysterectomized guinea-pigs were compared with those of similarly aged naturally formed corpora lutea 8 and 11 days after ovulation. The artificially induced bodies were smaller than normal corpora lutea, but grew to match their size after hysterectomy.

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