Experiments with antimalarial drugs in man
- 1 November 1957
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 51 (6) , 488-492
- https://doi.org/10.1016/0035-9203(57)90036-6
Abstract
10,732 and 10,580, metabolites respectively of 5943 and of proguanil, were found to be active antimalarial compounds, qualitatively similar to the parent compounds in their activity on all stages of the life cycle of P. falciparum. They are, however, very rapidly excreted and because of this are less suitable for use as antimalarial drugs than existing drugs.Keywords
This publication has 3 references indexed in Scilit:
- Experiments with antimalarial drugs in manTransactions of the Royal Society of Tropical Medicine and Hygiene, 1957
- A Metabolite of ‘Paludrine’ with High Antimalarial ActivityNature, 1951
- Activation of Paludrine in vitroNature, 1947