Abstract
Carefully controlled exptl. evidence is presented, based on studies in Uganda, that there are 2 definite epidemiological strains of yellow fever; one based on monkey-sylvan mosquito, and the other on man-domestic mosquito. In Africa the domestic form is Aedes simpsoni. In the area studied, A. africanus was the usual sylvan vector. A. simpsoni occasionally fed on monkeys and thereby acquired the virus they later spread to man. It seems logical that originally yellow fever was an animal disease and only secondarily became a disease of man. Jungle yellow fever is therefore the primitive form of the disease and appears to be identical in its behavior[long dash]whether in central Africa or in S. America. The vectors may vary but the cycle of existence and transfer is similar the world over.