THE ANTILIPAEMIC ACTIVITY OF LAMINARIN SULPHATE

Abstract
When rabbits were fed a diet containing 1% cholesterol the blood serum levels of neutral fat, phospholipid, free and esterified cholesterol, and β-lipoprotein were greatly increased. After the parenteral administration of laminarin sulphate or of heparin, all these were decreased, and the electrophoretic mobility of the β-lipoprotein was increased. Laminarin sulphate showed qualitatively the same effect as heparin on the hyperlipaemia. There was no clear relationship between the magnitude of dosage of either compound and the degree of its antilipaemic effect.