Effects of sodium selenite on methylmercury distribution in mice of late gestational period

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Abstract
Mercury distribution in pregnant mice, subcutaneously injected with 1.5 or 15.0 μmol/kg of methylmercury chloride (MeHg) and 0, 1.5 or 15.0 μmol/kg of sodium selenite, was investigated. Selenite increased the retention of mercury in maternal brain in every combination of doses. Selenite also increased mercury concentrations in maternal blood except one combination (MeHg 1.5; selenite 1.5 μmol/kg), and the increased mercury was partitioned to red blood cells. The increased mercury retention by selenite was also found in fetal brain.