Treatment of alopecia areata with dinitrochlorobenzene
- 1 July 1978
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 114 (7) , 1036-1038
- https://doi.org/10.1001/archderm.114.7.1036
Abstract
Persistent refractory alopecia areata in 26 patients was treated topically with dinitrochlorobenzene (DNCB). Sixteen patients have had excellent regrowth of hair; 3 patients could either not be initially sensitized or an adequate allergic contact dermatitis on the scalp did not develop. Two patients discontinued therapy within 2 mo.; hair growth did not develop in 5 patients despite an adequate trial. Augmentation of the T [thymus-derived] lymphocyte pool via DNCB sensitization and challenge may become effective therapy for some patients with severe alopecia areata.This publication has 2 references indexed in Scilit:
- Topical chemotherapy and immunotherapy of mycosis fungoides: intermediate-term resultsArchives of Dermatology, 1977
- Prednisone therapy for alopecia areata. A follow-up reportArchives of Dermatology, 1976