The Normal and Pathological Physiology of Brain Water

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Abstract
The physicochemical properties of water enable it to act as a solvent for electrolytes, and to influence the molecular configuration and hence the function— enzymatic in particular—of Polypeptide chains in biological systems. The association of water with electrolytes determines the osmotic regulation of cell volume and allows the establishment of the transmembrane ion concentration gradients that underlie nerve excitation and impulse conduction.