Cytotoxic T lymphocyte lines (CTLL) against a human minor alloantigen
- 1 January 1982
- journal article
- research article
- Published by Springer Nature in Immunogenetics
- Vol. 15 (5) , 501-508
- https://doi.org/10.1007/bf00345909
Abstract
Cytotoxic T-cell lines were generated following in vitro culture of lymphocytes from a patient suffering from aplastic anemia together with those of his HLA-identical brother, a repeated transfusion donor. The segregation pattern within the family of the determinant(s) detected by these cytotoxic cells strongly suggested that a minor alloantigen(s) was being detected. Testing of the effectors on a panel of unrelated individuals indicated that it was best seen in association with HLA-B7, which was common to both the patient and his sibling donor.This publication has 16 references indexed in Scilit:
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