Ring chromosome 2 in a child with growth failure and few congenital abnormalities
- 1 January 1980
- journal article
- case report
- Published by Wiley in American Journal of Medical Genetics
- Vol. 7 (3) , 383-389
- https://doi.org/10.1002/ajmg.1320070321
Abstract
A ring chromosome 2 mosaic [46,XX/46,XX,r(2)(p25q37)] was found in a newborn female with severe intrauterine growth retardation (IUGR), postnatal growth failure, and a few minor abnormalities. Psychomotor development has been normal to 19 months old. A ring chromosome 2 is present in 77.8% of the nuclei examined and is not found in the parents or a sibling. G- and R-banding reveal the break points to be p25q37. The presence of a normal cell line indicates that the chromosome abnormality arose after conception.Keywords
This publication has 1 reference indexed in Scilit:
- Three cases of ring chromosome 2, one derived from a paternal 2/6 translocationHuman Genetics, 1979