Targeting the beta‐catenin/APC pathway: a novel mechanism to explain the cyclooxygenase‐2‐independent anticarcinogenic effects of celecoxib in human colon carcinoma cells
Open Access
- 31 May 2005
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 19 (10) , 1353-1355
- https://doi.org/10.1096/fj.04-3274fje
Abstract
Celecoxib, a cyclooxygenase-2 (COX-2) selective nonsteroidal anti-inflammatory drug, is a new anticarcinogenic agent. Its antitumor effects depend on the one hand on its COX-2-inhibiting potency, but...Keywords
Funding Information
- Deutsche Forschungsgemeinschaft (GR2011/1‐1, GRK 757/1)
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