Tear and serum antibody levels in ocular herpetic infection: diagnostic precision of secretory IgA.
Open Access
- 1 August 1986
- journal article
- research article
- Published by BMJ in British Journal of Ophthalmology
- Vol. 70 (8) , 584-588
- https://doi.org/10.1136/bjo.70.8.584
Abstract
A sensitive enzyme linked immunosorbent assay (ELISA) was developed to evaluate the potential of herpes simplex virus (HSV) specific antibodies in the diagnosis of herpetic eye infection. The presence of HSV specific secretory IgA (sIgA) in tears was found to be diagnostic of infection. However, serum and tear HSV specific IgG and IgA were not considered reliable indicators of active infection.This publication has 15 references indexed in Scilit:
- Mucosal immunity and the eye.1985
- Prevalence of acute conjunctivitis caused by chlamydia, adenovirus, and herpes simplex virus in an ophthalmic casualty department.British Journal of Ophthalmology, 1984
- Secretory IgA specific for herpes simplex virus in lacrimal fluid from patients with herpes keratitis--a possible diagnostic parameter.British Journal of Ophthalmology, 1982
- HERPES-SIMPLEX VIRUS SPECIFIC SECRETORY IGA IN LACRIMAL FLUID DURING HERPES KERATITIS1982
- Herpes simplex virus specific secretory IgA in lacrimal fluid during herpes keratitisScandinavian Journal of Clinical and Laboratory Investigation, 1982
- 3,3′,5,5′-Tetramethylbenzidine as an Ames Test Negative Chromogen for Horse-Radish Peroxidase in Enzyme-ImmunoassayJournal of Immunoassay, 1981
- The use of a passive hemagglutionation test (PHA) in the diagnosis of viral eye diseasesAlbrecht von Graefes Archiv für Ophthalmologie, 1980
- Acute follicular conjunctivitis and keratoconjunctivitis due to herpes simplex virus in London.British Journal of Ophthalmology, 1978
- Immunoglobulins in TearsAmerican Journal of Ophthalmology, 1973
- The management of ocular herpes.1967