Effect of bilateral anterior cingulate damage in cats

Abstract
Bilateral anterior cingulate damage in 18 adult cats failed to produce any dramatic and persistant changes in behavior or any specific neurological syndrome. A study of cross sections and reconstructions of fixed brains showed that the mydriasis which occurred in 50% of the cats the day after surgery and disappeared within one to three days was associated with lesions that had extended into the olfactory zone. Abnormal hopping and placement reflexes, also common findings after surgery, were due to injuring projection fibers from the sensorimotor cortex and disappeared after about five days. A lack of appreciation of depth was correlated with inadvertently opening the ventricles and persisted for an average of four to five days post-operatively. Minor behavior changes of questional significance were transient.