Approaches to the Synthesis of Triterpenoids. II. Some Tetracyclic Precursors Suitable for Conversion into Pentacyclic Triterpenoids

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Abstract
The stereoselective total synthesis of several partially reduced chrysene derivatives, suitable as precursors for a variety of triterpenoids, is described. The key reaction in the most efficient route involves the highly stereoselective reductive alkylation of a cyclic α,β-unsaturated ketone with allyl bromide in lithium–ammonia, using water as a proton donor.

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